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Tewameter® TM Nano
Ultra-Small TEWL Probe for Precise Measurement on Special Skin Sites
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Overview
The Tewameter® TM Nano is an ultra-small TEWL measurement probe designed for assessing transepidermal water loss on very small, delicate, or difficult-to-access skin areas. Developed by Courage + Khazaka electronic GmbH, it provides objective and quantitative data for evaluating skin barrier function where standard TEWL probes may be too large.
With its small measurement diameter, the TM Nano is especially suitable for special skin sites, including small anatomical areas, curved surfaces, localized treatment zones, and animal skin studies. It is ideal for research applications where precise placement and minimal measurement area are required.
The TM Nano measures water evaporation from the skin surface and helps researchers evaluate barrier integrity, irritation potential, wound healing, treatment response, and product efficacy. It is particularly useful in dermatology, cosmetic research, pharmaceutical testing, and preclinical or small-area studies.
As part of the Courage + Khazaka Tewameter® family, the TM Nano complements standard TEWL probes such as the TM Hex, offering a specialized solution for small-site and high-precision TEWL measurements.
Features
Ultra-small 2 mm probe head
Allows precise TEWL measurement on very small or difficult skin sites such as nails, lips, scalp with hair, and small animal skin.
Open-chamber measurement principle
Provides TEWL values in g/h/m² without pressure, occlusion, or temperature accumulation on the measured area.
Reduced air turbulence
The small measurement chambers help minimize air turbulence inside the probe for more stable results.
Ideal for efficacy and safety testing
Suitable for cosmetic, dermatological, and pharmaceutical studies where barrier function, irritation, or product effects need to be evaluated on small areas.
Secure placement on curved surfaces
Special rubber rings help the probe sit tightly on slightly curved surfaces, such as nails.
Exchangeable hygienic rings
The rubber rings are removable and can be cleaned for hygienic use between measurements.
Stable sensor technology
New sensor technology supports precise, reliable, and stable TEWL measurements.
Easy calibration verification
Probe accuracy can be checked easily using the check calibration mode.
MPA system compatibility
The Tewameter® TM Nano can be connected to compatible Courage + Khazaka MPA systems.
Technology
The Tewameter® TM Nano measures transepidermal water loss (TEWL) using the established open-chamber diffusion principle. Water evaporating from the skin surface passes through the small measurement chamber, where sensors detect the water vapor gradient and calculate TEWL in g/h/m².
Its ultra-small 2 mm probe head allows the measurement chamber to be positioned precisely on very small or difficult-to-access areas. Because the open-chamber design does not seal the skin, it helps avoid pressure, occlusion, and temperature accumulation during measurement.
Application
Small and delicate skin sites
Ideal for TEWL measurement on small areas such as nails, lips, scalp with hair, and localized treatment zones.
Cosmetic efficacy and safety testing
Supports product evaluation, claim substantiation, irritation testing, and barrier function studies where a very small measurement area is required.
Dermatology and pharmaceutical research
Useful for studying barrier integrity, treatment response, wound healing, and skin recovery on special or difficult-to-access sites.
Animal and preclinical studies
Suitable for TEWL measurement on hairy or small animals, where standard TEWL probes may be too large.
Available Configuration
The Tewameter® TM Hex is available as a stand-alone MDD device, connectable to MPA systems depending on the required setup.
MPA
FAQs
What does the Tewameter® TM Nano measure?
The Tewameter® TM Nano measures transepidermal water loss (TEWL) in g/h/m², helping evaluate skin barrier function on very small or difficult-to-access sites.
What makes the TM Nano different from standard TEWL probes?
The TM Nano has an ultra-small 2 mm probe head, making it ideal for small areas such as nails, lips, scalp with hair, curved surfaces, and small animal skin.
Does the TM Nano use the open-chamber method?
Yes. The TM Nano uses the open-chamber measurement principle, allowing TEWL measurement without pressure, occlusion, or temperature accumulation on the measured skin site.
Can the TM Nano be used on curved surfaces?
Yes. Special rubber rings help the probe sit tightly on slightly curved surfaces, such as nails. The rings are exchangeable and can be cleaned for hygienic use.
Can the calibration of the TM Nano be checked?
Yes. The accurate calibration of the Tewameter® TM Nano can be easily verified using the check calibration mode, helping confirm reliable probe performance between regular calibration intervals.
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